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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP35 All Species: 5.76
Human Site: S121 Identified Species: 9.74
UniProt: Q8NFH5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFH5 NP_612142.2 326 34774 S121 P N I S V M Q S P L V G V T S
Chimpanzee Pan troglodytes XP_001160265 337 36129 E132 G I V P Y S K E C S S L E A R
Rhesus Macaque Macaca mulatta XP_001102848 326 34769 S121 P N I S V M Q S P L V G V T S
Dog Lupus familis XP_535992 406 43346 V201 S V M Q S P L V G V M T T T P
Cat Felis silvestris
Mouse Mus musculus Q8R4R6 325 34767 Q120 Q A N I S L L Q S P L V G A T
Rat Rattus norvegicus Q68FY1 325 34783 Q120 Q A N I S V L Q S P L V G V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516155 235 24557 A31 F L M G D L P A P A T P Q P R
Chicken Gallus gallus XP_421854 325 34473 P120 S F S L T Q S P L V G N M P S
Frog Xenopus laevis NP_001085157 318 33973 H112 T A N F S V L H T P L S G V M
Zebra Danio Brachydanio rerio Q6P6X9 308 32866 F103 L A A R K Q P F A G V H T P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573314 331 35081 L125 T P K K K N H L G M L Q L Q S
Honey Bee Apis mellifera XP_396287 584 64120 T379 R G A N T P N T S Q I V T E S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200424 554 60750 Q139 A P S R T P R Q L D S P A A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03790 475 52600 D198 L S S N I T F D G K P T A T P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 99.6 78 N.A. 92.9 94.4 N.A. 63.1 83.4 73.3 71.4 N.A. 27.1 22.6 N.A. 24.3
Protein Similarity: 100 95.8 100 79.3 N.A. 96 97.2 N.A. 65.9 91.4 84 82.2 N.A. 45 32.5 N.A. 36.4
P-Site Identity: 100 0 100 6.6 N.A. 0 0 N.A. 6.6 6.6 0 6.6 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 13.3 100 26.6 N.A. 20 20 N.A. 26.6 20 13.3 6.6 N.A. 26.6 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 29 15 0 0 0 0 8 8 8 0 0 15 22 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 8 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 0 0 0 0 8 8 0 % E
% Phe: 8 8 0 8 0 0 8 8 0 0 0 0 0 0 0 % F
% Gly: 8 8 0 8 0 0 0 0 22 8 8 15 22 0 0 % G
% His: 0 0 0 0 0 0 8 8 0 0 0 8 0 0 0 % H
% Ile: 0 8 15 15 8 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 8 8 15 0 8 0 0 8 0 0 0 0 0 % K
% Leu: 15 8 0 8 0 15 29 8 15 15 29 8 8 0 8 % L
% Met: 0 0 15 0 0 15 0 0 0 8 8 0 8 0 8 % M
% Asn: 0 15 22 15 0 8 8 0 0 0 0 8 0 0 0 % N
% Pro: 15 15 0 8 0 22 15 8 22 22 8 15 0 22 15 % P
% Gln: 15 0 0 8 0 15 15 22 0 8 0 8 8 8 0 % Q
% Arg: 8 0 0 15 0 0 8 0 0 0 0 0 0 0 15 % R
% Ser: 15 8 22 15 29 8 8 15 22 8 15 8 0 0 43 % S
% Thr: 15 0 0 0 22 8 0 8 8 0 8 15 22 29 15 % T
% Val: 0 8 8 0 15 15 0 8 0 15 22 22 15 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _